This is the story of a friendship that reflects the sexual freedom of the early LGBTQ movement of the 1970s. It’s also about how two friends responded in their own ways to a disaster that interrupted their lives. What do we do when life as we know it starts collapsing...

In August 1982, blood tests confirmed my worst fear: immune deficiency. Everything I’d read about AIDS convinced me I was doomed. Then my doctor, Joseph Sonnabend, told me that I might survive if I didn’t further tax my immune system by exposing myself to more STIs....

Pre-exposure prophylaxis, or PrEP for shorthand, is a new effort to prevent sexually transmitted AIDS by giving HIV medications to those who don’t have the virus but who are considered high risk for getting it. The first scientific PrEP study, known as iPREX, tested...

Background notes for the How to Have Sex in an Epidemic video interview clips that follow this post. In April 1983, as Michael Callen and I were nearing the completion of How to Have Sex in an Epidemic, I got an idea while watching Men and Films, Lou Maletta’s...